Nuclear medicine dosimetry.

نویسنده

  • Michael Stabin
چکیده

A brief overview is provided of the history of the development of internal dose methods for use in nuclear medicine. Basic methods of internal dosimetry and the systems that have been developed for use in nuclear medicine are described. The development of the MIRD system and the International Radiopharmaceutical Dosimetry Symposium series is outlined. The evolution of models and tools for calculating dose estimates is reviewed. Current efforts in developing more patient-specific methods, particularly for use in therapy calculations, development of small scale and microdosimetry techniques, and of relating internal radiation doses to observed biological effects are described and evaluated.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Whole body phantoms for the determination of dosimetry parameters needs for patients in nuclear medicine [Persian]

This study aims to give data concrning phantom material made in Iran i'rom a natural rubber which is used for obtaining calibration data for patient dose measurements in nuclear medicine applications of radionuclides for therapy and diagnosis. Is showed to be a tissue equivalent material cheap (25000 Rials the material itself and 35000 Rials the process of casting and moulding etc.), easi...

متن کامل

I-124 pre-therapy dosimetry for the treatment of differentiated thyroid cancer: A single center experience

Introduction:The maximum tolerable activity (MTA) of I-131 in radioiodine therapy is an established surrogate quantity to ensure that the therapeutic activity does not produce severe damages to the bone marrow and lung. The aim of this study was to estimate the MTAs for high-risk patients using I-124 pre-therapy dosimetry and to compare the results with published literature. <...

متن کامل

Rabbit internal dosimetry for iodine-131 using GATE Monte Carlo simulation code: a preclinical trial

Introduction: One of the main concerns in administration of radiotracers, especially in therapeutic arm, is the amount of delivered dose to the different organs. Individual variations of anatomy, physiology and underlying pathology in the patients lead to alteration of administered activity. In the current study we preclinically applied internal dosimetry using an animal mod...

متن کامل

Toward patient-friendly cell-level dosimetry.

Dosimetry for targeted radionuclide therapy is a relatively young field. Although initial work can be traced back to the late 1940s (1), the MIRD Committee formalism that forms the foundation for most current approaches was published in the mid 1970s (2), and the drive for improved dosimetry to meet the requirements of targeted radionuclide therapy did not begin until the 1980s. During this per...

متن کامل

Patient dose calculation software in nuclear medicine [Persian]

  Introduction: Radioactive materials deliver internal radiation dose to patients in nuclear medicine. Manual internal radiation dose assessment is a complicated method. Introduction of a simple dose calculation software is the main goal of the present study. Methods: Using the best current data in internal dose calculation (S-Factors) recommended by ICRP and by cons...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Physics in medicine and biology

دوره 51 13  شماره 

صفحات  -

تاریخ انتشار 2006